万南微，中共党员，博士，教授，硕士研究生导师。现任贵州省生物催化与手性药物合成重点实验室副主任，贵州省绿色制药工程研究中心主任。先后入选贵州第四批千人创新创业人才，贵州省省管专家，遵义市市管专家。先后获贵州省科技进步奖一等奖、贵州省研究生教学成果奖特等奖和贵州省高等教育教学成果一等奖各一项。主要从事绿色生物催化技术开发与应用研究，先后主持国家级科研项目3项，主持成果转化2项，以通讯作者在Angewandte Chemie International Edition、 ACS Catalysis、iScience、Advanced Synthesis & Catalysis等期刊上发表SCI论文10余篇。
联系方式: 564879895@qq.com; nanweiwan@zmu.edu.cn
近五年代表性科研项目
（1）遵义医科大学未来“科技菁英”人才培养计划，ZYSE-2022-03，2023-01-01至2027-12-31，210万元，在研，主持
（2）国家自然科学基金，22167023，卤醇脱卤酶催化C-N键构建新策略的定向调控及其催化机制的研究，2022-01-01至2025-12-31，36万元，在研，主持
（3）国家自然科学基金，31800663，卤醇脱卤酶不对称环化反应机制的研究，2019-01-01至2021-12-31，24万元，结题，主持
（4）国家自然科学基金，21662050，卤醇脱卤酶的筛选与改造及其在合成手性噁唑烷酮类化合物中的应用研究，2017-01-01至2020-12-31，40万元，结题，主持
（5）贵州省千人创新创业人才支持计划，2018-03至2021-03，50万元，结题，主持
近三年代表性科研成果
(1) Ran Ma, Xia Hua, Cheng-Li He, Hui-Hui Wang, Zhu-Xiang Wang, Bao-Dong Cui, Wen-Yong Han, Yong-Zheng Chen*, and Nan-Wei Wan*; Biocatalytic Thionation of Epoxides for Enantioselective Synthesis of Thiiranes, Angewandte Chemie International Edition, 2022, 61(52), e202212589. (2021 IF:16.8)
(
2) Qin Xu,
Kai-Shun Huang,
Yuan-Fei Wang, Hui-Hui Wang, Bao-Dong Cui, Wen-Yong Han,
Yong-Zheng Chen,*
and
Nan-Wei Wan*
; Stereodivergent Synthesis of Epoxides and Oxazolidinones via the Halohydrin Dehalogenase-Catalyzed Desymmetrization Strategy, ACS Catalysis,
2022
, 12(11): 6285−6293. (2021 IF:13.7)
(3) Hui-Hui Wang, Nan-Wei Wan, Run-Ping Miao, Cheng-Li He, Yong-Zheng Chen, Zhi-Qiang Liu,* and Yu-Guo Zheng; Identification and Structure Analysis of an Unusual Halohydrin Dehalogenase for Highly Chemo-, Regio- and Enantioselective Bio-Nitration of Epoxides; Angewandte Chemie International Edition, 2022, 61(37), e202205790. (2021 IF:16.8)
(4) Fang-Rui Zhang; Nan-Wei Wan*; Jin-Mei Ma; Bao-Dong Cui; Wen-Yong Han; Yong-Zheng Chen*; Enzymatic Kinetic Resolution of Bulky Spiro-Epoxyoxindoles via Halohydrin Dehalogenase-Catalyzed Enantio- and Regioselective Azidolysis, ACS Catalysis, 2021, 11(15): 9066-9072. (2021 IF:13.7)
(5) Jing-Fei Wu; Nan-Wei Wan*; Ying-Na Li; Qing-Ping Wang; Bao-Dong Cui; Wen-Yong Han; Yong-Zheng Chen*; Regiodivergent and stereoselective hydroxyazidation of alkenes by biocatalytic cascades, iScience, 2021, 24(8): 102883. (2021 IF:6.1)
(6) Xiao-Ying Zhou; Nan-Wei Wan*; Ying-Na Li; Ran Ma; Bao-Dong Cui; Wen-Yong Han; Yong-Zheng Chen*; Stereoselective Synthesis of Enantiopure Oxazolidinones via Biocatalytic Asymmetric Aminohydroxylation of Alkenes, Advanced Synthesis & Catalysis, 2021, 363(18): 43434-4348. (2021 IF:5.98)
(7) Nan-Wei Wan*; Xiao-Ying Zhou; Ran Ma; Jia-Wei Tian; Hui-Hui Wang; Bao-Dong Cui; Wen-Yong Han; Yong-Zheng Chen*; Synthesis of Chiral 5-Aryl-2-oxazolidinones via Halohydrin Dehalogenase-Catalyzed Enantio- and Regioselective Ring- Opening of Styrene Oxides, Advanced Synthesis & Catalysis, 2020, 362(5): 1201-1207. (2021 IF:5.98)
