崔宝东，中共党员，博士，教授，硕/博士生导师，贵州省高层次创新型人才“百”层次人选，贵州省高校优秀科技创新人才，贵州省“课程思政”示范课程教学名师，遵义市优秀科技工作者，遵义市市管专家，制药工程学科硕士点负责人，药学院教工第一党支部书记。研究方向包括：（1）有机分子与过渡金属组合催化的手性药物活性分子的不对称合成；（2）基于化学反应机制的生物酶催化新反应的设计与合成应用，主持省级和国家级教学改革项目各1项，获国家实验教学改革大赛二等奖1项；主持国家自然科学基金等省部级以上项目6项；在Chemical Communications、Advanced Synthesis & Catalysis, The Journal of Organic Chemistry等SCI收录期刊发表研究论文20余篇，获授权发明专利5件；先后获贵州省教育厅自然科学一等奖（排名第2）、贵州省科技进步一等奖（排名第3）、贵州省研究生教学成果特等奖（排名第3）、贵州省自然科学二等奖（排名第3）、贵州省药学科学技术奖三等奖（排名第1）。

代表性研究论文：

1. Ting Wang, Yong You, Zhen-Hua Wang, Jian-Qiang Zhao, Yan-Ping Zhang, Jun-Qing Yin, Ming-Qiang Zhou, Bao-Dong Cui,* Wei-Cheng Yuan*. Copper-Catalyzed Diastereo- and Enantioselective Decarboxylative [3 + 2] Cyclization of Alkyne-Substituted Cyclic Carbamates with Azlactones: Access to γ‑Butyrolactams Bearing Two Vicinal Tetrasubstituted Carbon Stereocenters. Org. Lett. 2023, DOI: 10.1021/acs.orglett.3c00075.

2. Yue-You Chen, Chen-Dong Zhou, Xing-Tong Li, Ting-You Yang, Wen-Yong Han, Nan-Wei Wan, Yong-Zheng Chen,* Bao-Dong Cui.* Cooperative Tertiary Amine/Palladium-Catalyzed Sequential [4 + 3] Cyclization/[1,3]-Rearrangement for Stereoselective Synthesis of Spiro [Methylenecyclopentane-1,3′-oxindolines]. J. Org. Chem. 2023, 88(1): 371-383.

3. Yan Long, Yun Wang, Yue-You Chen, Wen-Yong Han, Nan-Wei Wan, Wei-Cheng Yuan, Yong-Zheng Chen,* Bao-Dong Cui.* Copper-Catalyzed [5 + 1] Cyclization of o‑Pyrrolo Anilines and Heterocyclic N‑Tosylhydrazones for Access to Spirodihydropyrrolo[1,2‑a]quinoxaline Derivatives. J. Org. Chem. 2022, 87(6): 4112-4123.

4. Chao Zhang, You-Cai Wu, Bao-Dong Cui,* Lian Li, Wen-Yong Han, Nan-Wei Wan, Yong-Zheng Chen,* Palladium-Catalyzed Asymmetric Allylic Alkylation of 3-Aminooxindoles to Access Chiral Homoallylic Aminooxindoles. Org. Biomol. Chem. 2021, 19(21): 4720-4725.

5. You-Cai Wu, Bao-Dong Cui,* Yan Long, Wen-Yong Han, Nan-Wei Wan, Wei-Cheng Yuan, Yong-Zheng Chen,* Chiral Phosphoric Acid Catalyzed (4+1) Annulation of 3-Diazooxindoles/4-Diazooxisoquinolines with para-Quinone Methides to Access Chiral Spiro[dihydrobenzofuran-2,3'-oxindoles/2,4'-oxisoquinolines]. Adv. Synth. Catal. 2021, 363(6), 1702-1713.

6. Yu Chen, Bao-Dong Cui*, Yi Wang, Wen-Yong Han, Nan-Wei Wan, Mei Bai, Wei-Cheng Yuan, Yong-Zheng Chen*, Asymmetric [3 + 2] Cycloaddition Reaction of Isatin-Derived MBH Carbonates with 3-Methyleneoxindoles: Enantioselective Synthesis of 3,3'-Cyclopentenyldispirooxindoles Incorporating Two Adjacent Quaternary Spirostereocenters. J. Org. Chem. 2018, 83(17): 10465-10475.

7. Baodong Cui, Yu Chen, Jing Shan, Lei Qin, Changlun Yuan, Yi Wang, Wenyong Han, Nanwei Wan and Yongzheng Chen*. Enantioselective Synthesis of Spiro-oxindole-based 3,4-Dihydropyrroles via a Michael/Cyclization Cascade of 3-Aminooxindoles with 2-Enoylpyridines. Org. Biomol. Chem. 2017, 15(40): 8518-8522.

8. Baodong Cui, Jing Shan, Changlun Yuan, Wenyong Han, Nanwei Wan, Yongzheng Chen*. Synthesis of 2,3′-spirobi[indolin]-2-ones enabled by a tandem nucleophilic benzylation/C(sp²)-N cross-coupling reaction sequence. Org. Biomol. Chem. 2017, 15(28): 5887-5892.

9. Tinglei Zhang, Baodong Cui*, Wenyong Han, Nanwei Wan, Mei Bai, Yongzheng Chen*. Sequential Nucleophilic C(sp³)-Benzylation/C(sp²)-H Arylation for the Synthesis of Spiro[oxindole-3,5′-pyrrolo[2,1-a]isoquinolines]. Eur. J. Org. Chem. 2017, 2017(22): 3179-3186.

10. Jing Shan, Baodong Cui*, Yu Wang, Chengli Yang, Xiaojian Zhou, Wenyong Han, Yongzheng Chen*. Organocatalytic Asymmetric Mannich Reaction of 3-Hydroxyoxindoles/3-Aminooxindoles with in Situ Generated N-Boc-Protected Aldimines for the Synthesis of Vicinal Oxindole-Diamines/Amino Alcohols. J. Org. Chem. 2016, 81(13): 5270-5277.

11. Yong You, Bao-Dong Cui (并列第一作者), Ming-Qiang Zhou, Jian Zuo, Jian-Qiang Zhao, Xiao-Ying Xu, Xiao-Mei Zhang, Wei-Cheng Yuan*. Organocatalytic Asymmetric Michael/Friedel-Crafts Cascade Reaction of 3-Pyrrolyl-oxindoles and α,β-Unsaturated Aldehydes for the Construction of Chiral Spiro[5,6-dihydropyrido[1,2-a]pyrrole-3,3′-oxindoles]. J. Org. Chem. 2015, 80, 5951-5957.

12. Bao-Dong Cui, Yong You, Jian-Qiang Zhao, Jian Zuo, Zhi-Jun Wu, Xiao-Ying Xu, Xiao-Mei Zhang, Wei-Cheng Yuan*. 3-Pyrrolyl-oxindoles as efficient nucleophiles for organocatalytic asymmetric synthesis of structurally diverse 3,3′-disubstituted oxindole derivatives. Chem. Commun. 2015, 51, 757-760.

13. Bao-Dong Cui, Jian Zuo, Jian-Qiang Zhao, Ming-Qiang Zhou, Zhi-Jun Wu, Xiao-Mei Zhang, Wei-Cheng Yuan*. Tandem Michael Addition-Ring Transformation Reactions of 3Hydroxyoxindoles/3-Aminooxindoles with Olefinic Azlactones: Direct Access to Structurally Diverse Spirocyclic Oxindoles. J. Org. Chem. 2014, 79, 5305-5314.

14. Bao-Dong Cui, Wen-Yong Han, Zhi-Jun Wu, Xiao-Mei Zhang, Wei-Cheng Yuan*. Enantioselective Synthesis of Quaternary 3-Aminooxindoles via Organocatalytic Asymmetric Michael Addition of 3-Monosubstituted 3-Aminooxindoles to Nitroolefins. J. Org. Chem. 2013, 78, 8833-8839.

主持科研项目：

1. 贵州省高层次创新型人才百层次人员，黔科合平台人才-GCC[2022]032-1，2022/07-2025/07，120万元。

2. 国家自然科学基金项目，22261056，基于2-羟甲基烯丙酯新反应性的组合催化反应设计与合成应用，2023/01-2026/12，33万元。

3. 国家自然科学基金项目，21907114，P450酶催化卡宾对N-H/O-H键的插入串联反应的设计、催化机制与合成应用，2020/01-2022/12，24万元。

4. 国家自然科学基金项目，名称：Pd催化“一锅”法不对称合成手性螺环四氢吲嗪类化合物的研究，编号：21662049，年限：2017.01—2020.12，41万元。

5. 贵州省科学技术基金重点项目，名称：手性螺环四氢吲嗪类化合物的组合催化合成与应用研究，编号：黔科合基础[2016]1421，年限：2016.10—2020.10，30万元。

6. 教育部春晖计划项目，名称：手性螺[二氢呋喃-氧化吲哚]类衍生物的不对称合成与应用研究，编号：Z2016005，年限：2017.01—2019.12，3万元。

7. 贵州省社会发展公关项目，名称：G56、沙格列汀等化学创新药及仿制药研究与开发，编号：黔科合SY[2015]3030，年限：2015.01—2018.06，30万元。

8. 遵义医科大学青年优秀人才，17zy-005号，2017/10-2022/10，75万元。