序号

论文题目

期刊名称, 年，卷, 起止页码

期刊影响因子

分区（JCR）

成果主要完成人

1

Trifluoromethyl Rhodium-Carbynoid in [2+1+2] Cycloadditions

Angew. Chem. Int. Edit. 2024, 63, e202318887

16.1

Q1

韩文勇，陈永正

2

Iodomethane in C1 chemistry: application in palladium-catalyzed [2+2+1] annulation

Org. Biomol. Chem., 2024, 22, 3204-3208

2.9

Q1

韩文勇，陈永正

3

De Novo Synthesis of a-Ketoamides via Pd/TBD Synergistic Catalysis

advance science, 2024, 10.1002/advs.202404266

14.3

Q1

陈永正，韩文勇

4

Biocatalytic Construction of Spiro-Oxazolidinones via Halohydrin Dehalogenase-Catalyzed Ring Expansion of Spiro-Epoxides

ACS Catal. 2024, 14, 14, 10670–10678

11.3

Q1

万南微，陈永正

5

Sequential Ring Opening/In Situ SO2Capture/Alkynylation of
Cyclopropanols with Alkynyl Triflones Initiated by Energy Transfer

J. Org. Chem. 2024, 89, 7656−7661

3.4

Q2

刘小卒，刘培均

6

Catalyst-Free α-trans-Selective Hydroboration and (E)-Selective Deuterated Semihydrogenation of Alkynyl Sulfones

J. Org. Chem. 2024, 89, 8326–8333

3.4

Q2

刘小卒，刘培均

7

Halogen-Bond-Promoted Direct Cross-Coupling of Trifluoromethylated Alkyl Bromides with Coumarins/Quinolinones: Unraveling Trifluoromethyl Effects

Org. Lett. 2024, 26, 3097-3102

4.9

Q1

贺春阳

8

Halogen-Bond-Promoted Direct Cross-Coupling of Ethyl 3-bromo-3-alkyl-2,2-difluoropropanoate with Coumarins/Quinolinones

Org. Chem. Front.2024,11, 3320-3325

4.6

Q1

贺春阳

9

Catalytic Reduction of Trifluoromethylated Alkyl Bromides and Synthesis of Alkylated Heterocycles under Visible Irradiation: Synergetic Action of Halogen Bond and Ni Catalysis

Org. Chem. Front.2024, DOI: 10.1039/D4QO00966E

4.6

Q1

贺春阳

10

Catalyst-free Decarboxylative Cross-Coupling of N-hydroxyphthalimide Esters with tert-Butyl 2-(trifluoromethyl)acrylate and Its Application

Org. Biomol. Chem. 2024, 22, 2279-2283

2.9

Q3

贺春阳

11

Iron(II)-Catalyzed Radical [3+2] Cyclization of N-Aryl Cyclopropylamines for the Synthesis of Polyfunctionalized Cyclopentylamines

Org. Lett. 2024, 26,  3151–3157

4.9

Q1

崔宝东, 陈永正

12

2,2′-Bipyridine-Enabled Photocatalytic Radical [4+2] Cyclization of N-Aryl-α-amino Acids for Synthesizing Polysubstituted Tetrahydroquinolines

Org. Lett. 2024, 26, 3195–3201

4.9

Q1

崔宝东, 陈永正

13

Regioselective and enantioselective propargylic hydroxylations catalyzed by P450tol monooxygenases

Bioresour. Bioprocess., 2024, 11, 64

4.3

Q1

周晓建，陈永正

14

Teacher–student relationships and student engagement: The mediating effect of peer relationships

Social Behavior and Personality，2024, 52(5), e13104

1.0

Q4

王中强

15

Synthesis of Chiral Sulfoxides by A Cyclic Oxidation-Reduction Multi-Enzymatic Cascade Biocatalysis

Chemistry - A European Journal ，2024, 30, e202304081

3.9

Q1

杨加伟，陈永正

16

Engineering of methionine sulfoxide reductase A with simultaneously improved stability and activity for kinetic resolution of chiral sulfoxides

International Journal of Biological Macromolecules, 2024, 260, 129540

7.7

Q1

杨加伟，陈永正

17

Photoredox-Catalyzed Intramolecular Oxy- and Aminoacylation of Alkenes with Acyl Oxime Esters: Facile Synthesis of Acylated Saturated Heterocycles

Organic Chemistry Frontiers 2024, 11，74-82.

4.6

Q1

牟学清，陈永正

18

Coffee charcoal as a green catalyst for oxidative dehydrogenation

Chemical Engineering Journal，2024，479：147784

13.3

Q1

张世明，陈永正

19

Constructing a CdS QDs/silica gel composite with high photosensitivity and prolonged recyclable operability for enhanced visible-light-driven NADH regeneration

Journal of Colloid And Interface Science，2023，652：1043-1052

9.4

Q1

张世明，陈永正

20

A facile one-pot synthesis of N-acyl-1-cyano-1,2,3,4-tetrahydroisoquinoline via a photoredox and Reissert-type reaction from 1,2,3,4-tetrahydroisoquinolines.

New Journal of Chemistry 2023, 47, 15847-15851.

2.7

Q2

张韵，陈永正

21

Cooperative Tertiary Amine/Palladium-Catalyzed Sequential [4 + 3] Cyclization/[1,3]-Rearrangement for Stereoselective Synthesis of Spiro [Methylenecyclopentane-1,3′-oxindolines]

J. Org. Chem. 2023, 88, 1, 371–383

3.3

Q2

陈永正，崔宝东

22

Copper-Catalyzed Diastereo- and Enantioselective Decarboxylative [3 + 2] Cyclization of Alkyne-Substituted Cyclic Carbamates with Azlactones: Access to γ-Butyrolactams Bearing Two Vicinal Tetrasubstituted Carbon Stereocenters

Org. Lett. 2023, 25, 8, 1274–1279

4.9

Q1

崔宝东

23

Biocatalytic Enantioselective Synthesis of Chiral β-Hydroxy Nitriles Using Cyanohydrins as Cyano Sources

ACS Catal. 2023, 13, 13597−13606

12.9

Q1

万南微，陈永正

24

Biocatalytic Synthesis of Metaxalone and Its Analogues

Org. Lett. 2023, 25, 27, 5049–5054

4.9

Q1

万南微，陈永正

25

Asymmetric Bio-Epoxidation of Unactivated Alkenes

ChemBioChem 2023, 24, e202200719

2.6

Q2

周晓建，陈永正

26

Toward the Generation of 2-Amino-3-Formyl Difunctionalized Chromones via Pd-Enabled Rearrangement Strategy

ACS Catal. 2023, 13, 19, 12692–12699

12.9

Q1

韩文勇，陈永正

27

Palladium-catalyzed decarboxylation [2+2+2] annulation approach to chromone-containing polycyclic compounds

Org. Chem. Front., 2023,10, 3752-3759

5.4

Q1

韩文勇，陈永正

28

Electrochemically Enabled Intramolecular Amino- and Oxysulfonylation of Alkenes with Sodium Sulfinates to Access Sulfonylated Saturated Heterocycles

J. Org. Chem. 2023, 88, 3238−3253

3.6

Q2

牟学清，陈永正

29

Identification of novel aminopyrimidine derivatives for the treatment of mutant NSCLC

European Journal of Medicinal Chemistry, 2023, 265, 116074

6.0

Q1

祁宝辉

30

Biocatalytic hydroxylation tertiary C-H bonds for synthesis of chiral tertiary alcohols by cytochrome P450

Molecular Catalysis, 2023, 553, 113791

3.9

Q1

陈永正

31

Enantiodivergent Synthesis of Halohydrins by Engineering P450DA Monooxygenases

ACS Catal., 2023,13,15948–15955

12.9

Q1

周晓建，陈永正

32

Design, synthesis and biological evaluation of EGFR kinase inhibitors that spans the orthosteric and allosteric sites

Bioorganic & Medicinal Chemistry, 2023, 96, 117534

3.3

Q1

祁宝辉

33

Et2Zn-Mediated Radical (3+2) Cycloaddition of Vinyl Azides with Ethyl Iododifluoroacetate to Access 3,3-Difluoro-γ-lactams

J. Org. Chem. 2023,  88, 14634–14639

3.3

Q2

刘小卒，刘培均

34

Backbone N-methylation of peptides: Advances in synthesis and applications in pharmaceutical drug development

Bioorganic Chemistry, 2023, 141, 106892

4.5

Q1

贺春阳

35

Substituent-controlled site-selective silylation of 2H-indazoles to access silylated 1H-indazoles and 2H-indazoles under transition metal-free conditions

Org. Chem. Front., 2023,10, 5389-5394

4.6

Q1

贺春阳

36

Synthesis of Alkylated Polyfluorobenzenes through Decarboxylative Giese Addition of Aliphatic N-Hydroxyphthalimide Esters with Polyfluorostyrene

J. Org. Chem. 2023, 88, 14105–14114

3.3

Q2

贺春阳

37

Synthesis of Secondary Trifluoromethyl Boronic Esters through Visible Light Induced Decarboxylative Alkylation Reactions

Advanced Synthesis & Catalysis, 2023, 365, 1596-1601

4.4

Q1

贺春阳

38

Synthesis of Fluoroalkylated Pyrrolidines through Neat Reaction of Fluoroalkyl Iodides with N, N-Diallylamines

Advanced Synthesis & Catalysis, 2023, 365, 3063-3068

4.4

Q1

贺春阳

39

Kinetic resolution of sulfoxides with high enantioselectivity using a new homologue of methionine sulfoxide reductase B

Org. Biomol. Chem., 2023, 21, 7873-7879

2.9

Q1

杨家伟，陈永正

40

Photocatalytic Decarboxylative Coupling of Aliphatic N-Hydroxyphthalimide Esters with Bromopolyfluorobenzene

Advanced Synthesis & Catalysis, 2023, 365, 854-859

4.4

Q1

贺春阳

41

Mice kidney biometabolic process analysis after cantharidin exposure using widely-targeted metabolomics combined with network pharmacology

Food and Chemical Toxicology. 2023, 171, 113541

4.3

Q1

何天目，李晓飞，张建永

42

Integrated metabolomics and network pharmacology revealing the mechanism of arsenic-induced hepatotoxicity in mice

Food and Chemical Toxicology. 2023, 178, 113913

4.3

Q1

王雅芝，张建永

43

Integration of metabolomics and network pharmacology to reveal the protective mechanism underlying Wogonoside on acute myocardial ischemia rats

Journal of Ethnopharmacology, 2023, 317, 116871

4.8

Q1

冯文忠，张建永

44

Gold Nanoparticles Coated with SH-PEG-NH2 and Loaded with Ziyuglycoside I for Promoting Autophagy in Hematopoietic Stem Cells

International Journal of Nanomedicine. 2023 ,18:1347-1362.

8.0

Q1

熊永爱，蔡荣珊

45

The emerging role of PANoptosis in cancer treatment

Biomedicine&Pharmacotherapy. 2023,168:115696

7.5

Q1

熊永爱

46

Polydopamine-coated mesoporous silica nanoparticles co-loaded with Ziyuglycoside I and Oseltamivir for synergistic treatment of viral pneumonia

International Journal of Pharmaceutics.2023 ,645:123412.

5.8

Q1

王宏，熊永爱

47

Biocatalytic Thionation of Epoxides for Enantioselective Synthesis of Thiiranes

Angew. Chem. Int. Ed. 2022, 61, e202212589

16.8

Q1

马冉，万南微，陈永正

48

Identification and Structure Analysis of an Unusual Halohydrin Dehalogenase for Highly Chemo-, Regio- and Enantioselective Bio-Nitration of Epoxides

Angew. Chem. Int. Ed. 2022, 61, e202205790

16.8

Q1

王慧慧，万南微，陈永正

49

Multienzyme Redox System with Cofactor Regeneration for Cyclic Deracemization of Sulfoxides

Angew. Chem. Int. Ed.  2022, 61, e202209272

16.8

Q1

杨加伟，陈永正

50

Stereodivergent Synthesis of Epoxides and Oxazolidinones via theHalohydrin Dehalogenase-Catalyzed Desymmetrization

ACS Catal. 2022, 12, 6285-6293

13.7

Q1

陈永正，万南微

51

Monitoring the different changing behaviors of center dot OH and cysteine in two ferroptosis pathways by a dual-functional fluorescence probe

Sens. Actuators, B, 2022, 362, 131742.

9.2

Q1

李洪玉，袁泽利

52

Complementary Copper-Catalyzed and Electrochemical Aminosulfonylation of OHomoallyl Benzimidates and NAlkenyl Amidines with Sodium Sulfinates

Organic Letters，2022, 24, 1405−1411

5.2

Q1

牟学清，陈永正

53

Identification of (S)-1-(2-(2,4-difluorophenyl)-4-oxothiazolidin-3-yl)-3-(4-((7-(3-(4-ethylpiperazin-1-yl)propoxy)-6-methoxyquinolin-4-yl) oxy)-3,5-difluorophenyl)urea as a potential anti-colorectal cancer agent

Eur. J. Med. Chem. 2022, 239, 114561

7.1

Q1

祁宝辉

54

Dual target inhibitors based on EGFR: Promising anticancer agents for the treatment of cancers (2017-)

Eur. J. Med. Chem. 2022, 227, 113963.

7.1

Q1

祁宝辉

55

Nickel-Catalyzed Cross-Coupling of Amino-Acid-Derived Alkylzinc Reagents with Alkyl Bromides/Chlorides: Access to Diverse Unnatural Amino Acids

Org. Lett. 2022, 24, 240-244

6.1

Q1

贺春阳

56

Synthesis of Secondary Trifluoromethylated Alkyl Bromides Using 2-Bromo-3,3,3-trifluoropropene as a Radical Acceptor

Org. Lett. 2022, 24, 2143-2148

6.1

Q1

贺春阳

57

Cu-Catalyzed Asymmetric 1,3-Dipolar Cycloaddition of N-2,2,2-Trifluoroethylisatin Ketimines Enables the Desymmetrization of N-Arylmaleimides: Access to Enantioenriched F3C-Containing Octahydropyrrolo[3,4-c]pyrroles

Org. Lett. 2022, 24, 4052-4057.

6.1

Q1

韩文勇，袁伟成

58

Catalytic Enantioselective Dearomatization/Rearomatization of 2-Nitroindoles to Access 3-Indolyl-3 '-Aryl-/Alkyloxindoles: Application in the Formal Synthesis of Cyclotryptamine Alkaloids

Org. Lett. 2020, 22, 7088-7093.

6.1

Q1

周晓建，陈永正，袁伟成

59

Visible-Light-Induced Regioselective Deaminative Alkylation of Coumarins via Photoredox Catalysis

Adv. Synth. Catal. 2022, 364, 24-29

6.0

Q1

贺春阳

60

Copper-Catalyzed [5+1] Cyclization of o-Pyrrolo Anilines and Heterocyclic N-Tosylhydrazones for Access to Spiro-dihydropyrrolo[1,2-a]quinoxaline Derivatives

J. Org. Chem. 2022, 87, 4112-4123

4.2

Q1

陈永正，崔宝东

61

Access to 4-Trifluoromethyl Quinolines via Cu-Catalyzed AnnulationReaction of Ketone Oxime Acetates withortho-TrifluoroacetylAnilines under Redox-Neutral Conditions

J. Org. Chem. 2022, 87, 5804-5816.

4.2

Q1

袁伟成

62

Copper-Catalyzed Ring-Opening (3+2) Annulation of Cyclopropenones with Ketoxime Acetates: Access to 1,2-Dihydro-pyrrol-3-ones Bearing a Quaternary Carbon Center

Eur. J. Org. Chem. 2022, e202200110.

3.3

Q2

袁伟成

63

EGFR-based dual inhibitors: current status and perspectives

Future Med. Chem. 2022, 14, 601-603

4.8

Q2

祁宝辉

64

Identification of 1,3-thiazinan-4-one urea-based derivatives as potent FLT3/VEGFR2 dual inhibitors for the treatment of acute myeloid leukemia

J. Mol. Struc. 2022, 1250, 131862.

3.8

Q3

祁宝辉

65

Organocatalyzed asymmetric dearomative 1,3-dipolar cycloaddition of 2-nitrobenzofurans and N-2,2,2-trifluoroethylisatin ketimines

Chirality. 2022, 34, 1019-1034.

2.2

Q3

周晓建，袁伟成

66

Visible-light promoted cross-coupling of ethyl iododifluoroacetate with silyl enol ethers for the synthesis of β-fluoroenones via noncovalent interactions

Tetrahedron Lett. 2022, 97, 153782

2.0

Q3

贺春阳

67

Transition-metal-free, direct Csingle bondH radical trifluoromethylation of nitroimidazoles with Togni’s reagent

Tetrahedron Lett. 2022, 92, 153659

2.0

Q3

王京，陈永正，张磊

68

Efficacious removal of trace mercury from honeysuckle water decoction using multifunctional mesoporous carbon

ACS Omega, 2022, 7, 46787-46797

4.1

Q2

张建永，余明

69

Bibliometric and visual analysis of nephrotoxicity research worldwide

Frontier Pharmacology, 2022, 13, 940791.

6.0

Q1

张建永，李晓飞

70

Discovery of novel conjugates of quinoline and thiazolidinone urea as potential anti-colorectal cancer agent

J. Enzyme Inhib. Med. Chem. 2022, 37, 2334–2347

5.8

Q1

祁宝辉

71

Exploring the protective mechanisms of total tannins from Geum japonicum var. chinense F.Bolle in mice with hematopoietic dysfunction via the JAK2/STAT3/5 signaling pathway

Journal of Ethnopharmacology, 2022, 1, 115507

5.2

Q1

张建永，段灿灿

72

Directed evolution of cytochrome P450DA hydroxylase activity for stereoselective biohydroxylation

Catal. Sci. Technol. 2022,12, 5703-5708

6.2

Q2

万南微，陈永正

73

Enzyme-catalyzed allylic oxidation reactions: A mini-review

Front. Chem. 2022, 10, 950149

5.5

Q2

陈永正

74

Hepatotoxicity of cantharidin is associated with the altered bile acid metabolism

Journal of Applied Toxicology, 2022, 42, 970-980

3.6

Q2

张建永

75

Enzymatic approaches to site-selective oxidation of quinoline and derivatives

Org. Biomol. Chem. 2022, 20, 2580-2600

3.9

Q2

陈永正

76

Radical borylation of vinyl azides with NHC-boranes: divergent synthesis of alpha-boryl ketones and borylated triazoles

Org. Biomol. Chem. 2022, 20, 3550-3557

3.9

Q2

刘培均，刘小卒

77

Catalyst-free photo-reductions of aromatic olefins and carbonyl compounds

Org. Biomol. Chem. 2022, doi: 10.1039/D2OB01353C

3.9

Q2

姚秋丽

78

Highly Enantioselective Hydroxylation of 3-Arylpropanenitriles to Access Chiral beta-Hydroxy Nitriles by Engineering of P450pyr Monooxygenase

Org. Process Res. Dev. 2022, 26, 2046−2051

3.9

Q1

陈永正

79

Pharmacological profiles and therapeutic applications of pachymic acid (Review)

Exp. Ther. Med. 2022, 24, 547

2.8

Q4

张磊

80

Endoplasmic reticulum stress contributes to autophagy and apoptosis in cantharidin-induced nephrotoxicity

Food and Chemical Toxicology,2022,163, 112986

5.6

Q1

张建永，段灿灿

81

Effective Material Basis and Mechanism Analysis of Compound Banmao Capsule Against Tumors using Integrative Network Pharmacology and Molecular docking

Evidence-Based Complementary and Alternative Medicine, 2021, 2021, 6653460

2.7

Q3

何天目，李晓飞，张建永

82

The crosstalk betweencaspases family and cGAS-STING signaling pathway

Journal of Molecular Cell Biology. 2021,13(10):739-747.

8.2

Q1

熊永爱

83

TPGS-Modified Long-Circulating Liposomes Loading Ziyuglycoside I for Enhanced Therapy of Myelosuppression.

International Journal of Nanomedicine. 2021,16:6281-6295.

8.0

Q1

宋婷婷，熊永爱

84

Enzymatic Kinetic Resolution of Bulky Spiro-Epoxyoxindoles via Halohydrin Dehalogenase-Catalyzed Enantio- and Regioselective Azidolysis

ACS Catal. 2021, 11, 9066-9072

13.7

Q1

万南微，陈永正

85

Hypervalent Iodine-mediated gem-difluorination of Vinyl Halides Enabled by Exclusive 1,2-halo Migration

Sci. China Chem. 2021, 64, 999-1003

10.1

Q1

刘培均

86

Anticancer potential of indirubins in medicinal chemistry: Biological activity, structural modification, and structure-activity relationship

Eur. J. Med. Chem. 2021, 223, 113652

7.1

Q1

张磊，陈永正

87

Regiodivergent and Stereoselective Hydroxyazidationof Alkenes by Biocatalytic Cascades

iScience, 2021, 24, 102883

6.1

Q1

万南微，陈永正

88

Diazotrifluoroethyl Radical: A CF3Containing Building Block in [3+2] Cycloaddition

Org. Lett. 2021, 23, 9256-9261

6.1

Q1

韩文勇，陈永正

89

Chiral Phosphoric Acid Catalyzed (4+1) Annulation of 3-Diazooxindoles/4-Diazooxisoquinolines with para-Quinone Methides to Access Chiral Spiro[dihydrobenzofuran-2,3'-oxindoles/2,4'-oxisoquinolines]

Adv. Synth. Catal. 2021, 363, 1702-1713

6.0

Q1

崔宝东，陈永正

90

Stereoselective Synthesis of Enantiopure Oxazolidinones via Biocatalytic Asymmetric Aminohydroxylation of Alkenes

Adv. Synth. Catal. 2021, 363, 4343-4348

6.0

Q1

万南微，陈永正

91

Aziridine used as a Vinylidene Unit in Palladium-catalyzed [2 + 2 + 1] Domino Annulation

Org. Chem. Front. 2021, 8, 3413-3420

5.5

Q1

韩文勇，陈永正

92

Catalyst-free Reductive Hydrogenation or Deuteration of Aryl–heteroatom Bonds Induced by Light

Org. Chem. Front. 2021, 8, 5244-5249

5.5

Q1

姚秋丽

93

Palladium-catalyzed [2 + 2 + 1] Annulation: Access to Chromone Fused Cyclopentanones with Cyclopropenone as the CO Source

Org. Chem. Front. 2021, 8, 3082-3090

5.5

Q1

韩文勇，陈永正

94

Visible light induced deaminative alkylation of difluoroenoxysilanes: a transition metal free strategy

Org. Chem. Front. 2021, 8, 4438-4444

5.5

Q1

贺春阳

95

Iron-catalyzed C-F bond silylation and borylation of fluoroarenes

Org. Chem. Front. 2021, 8, 5322-5327

5.5

Q1

贺春阳

96

Discovery of 4-((4-(4-(3-(2-(2,6-difluorophenyl)-4-oxothiazolidin-3-yl)ureido)-2-fluorophenoxy)-6-methoxyquinolin-7-yl)oxy)-N,N-diethylpiperidine-1-carboxamide as kinase inhibitor for the treatment of colorectal cancer

Bioorg. Chem. 2021,106, 104511.

5.3

Q1

祁宝辉

97

Copper-Catalyzed Decarboxylative [3+2] Annulation of Ethynylethylene Carbonates with Azlactones: Access to gamma-Butyrolactones Bearing Two Vicinal Quaternary Carbon Centers

J. Org. Chem. 2021, 86, 1779-1788.

4.2

Q1

王云（硕士生），袁伟成

98

Catalyst-Free Generation of Acyl Radicals Induced by Visible Light in Water to Construct C–N Bonds

Org. Biomol. Chem. 2021, 19, 1970-1975

3.9

Q1

姚秋丽

99

Palladium-Catalyzed Asymmetric Allylic Alkylation of 3-Aminooxindoles to Access Chiral Homoallylic Aminooxindoles

Org. Biomol. Chem. 2021, 19, 4720-4725

3.9

Q2

崔宝东，陈永正

100

Cu(I)-N-heterocyclic carbene-catalyzed base free C-N bond formation of arylboronic acids with amines and azoles

Tetrahedron, 2021, 79, 131861

2.4

Q2

史大斌

101

Visible-light-promoted late-stage direct fluoroalkylation of nitroimidazoles

Tetrahedron Lett. 2021, 85, 153484

2.0

Q3

王京，陈永正，张磊

102

Palladium-Catalyzed Cross-Coupling of Benzylzinc Reagents with 2-Bromo-3,3,3-Trifluoropropene

Synth. Commun. 2019, 49, 3329-3334

1.9

Q3

贺春阳

103

Atom transfer radical additions (ATRAs) promoted by catalytic amounts of amines: The effective iododifluoroalkylation of alkenes/alkynes

Synth. Commun. 2021, 51, 2016-2024

1.9

Q3

赵亮

104

Recent Advance in the Transition-Metal Free Coupling Reactions for the Construction of C-X Bonds Induced by Light

Chin. J. Org. Chem. 2019, 39, 1583-1595

0.4

Q3

姚秋丽

105

106

Thermodynamic Analysis of Tyrosyl-tRNA Synthetases Revealed Bacterial-Selective Tyrosine Derivatives

Aust. J. Chem. 2021, 74, 740-745

1.2

Q4

王中强

107

Analysis of cantharidin-induced nephrotoxicity in HK-2 cells using untargeted metabolomics and an integrative network pharmacology analysis

Food and Chemical Toxicology, 2020, 146, 111845

6.0

Q1

李晓飞，张建永

108

A novel approach combining metabolomics and molecular pharmacology to study the effect of Gei Herba on mouse hematopoietic function

Biomedicine & Pharmacotherapy, 2020, 129, 110437

6.5

Q1

段灿灿，张建永

109

Hepatoxicity mechanism of cantharidin-induced liver LO2 cells by LC–MS metabolomics combined traditional approaches

Toxicology Letters, 2020, 333, 49–61

4.4

Q2

张建永，李晓飞

110

Cantharidin induced LO2 cell autophagy and apoptosis via endoplasmic reticulum stress pathway in vitro

Journal of applied toxicology, 2020, 40, 1622-1635

3.4

Q2

张建永，李晓飞

111

Study on the mechanism of cantharidin-induced hepatotoxicity in rat using serum and liver metabolomics combined with conventional pathology methods

Journal of applied toxicology. 2020, 40, 1259-1271

3.4

Q2

张建永，段灿灿，李晓飞

112

Protective effects of aqueous extract from Gei Herba on blood-deficiency mice: insights gained by a metabolomic approach

RSC advances, 2020, 10, 10167-10177

3.4

Q2

段灿灿，张建永

113

Transition-metal-free radical relay cyclization of vinyl azides with 1,4-dihydropyridines involving a 1,5-hydrogen-atom transfer: access to alpha-tetralone scaffolds

Org. Chem. Front. 2020, 7, 3638-3647

5.5

Q1

刘培均，刘小卒

114

Difluoroalkylation of alkenes promoted by noncovalent interaction: A general method for the synthesis of difluoro-contained dihydrobenzofurans and indolins

Tetrahedron Lett. 2020, 61, 152558

2.0

Q3

赵亮，贺春阳

115

Base-mediated [4+2] annulation of electron-deficient nitrobenzoheterocycles and alpha,alpha-dicyanoalkenes in water: Facile access to structurally diverse functionalized dibenzoheterocyclic compounds

Tetrahedron 2020, 76, 131115.

2.4

Q2

陈永正，袁伟成

116

Discovery and application of methionine sulfoxide reductase B for preparation of (S)-sulfoxides through kinetic resolution

Catal. Commun. 2020, 136, 105908

3.5

Q3

杨加伟

117

Characterization of a Self-Sufficient Cytochrome P450 Monooxygenase from Deinococcus apachensis for Enantioselective Benzylic Hydroxylation

ChemBioChem, 2020, 21, 1820-1825

3.5

Q3

万南微，陈永正

118

Visible-light Promoted Atom Transfer Radical Addition-Elimination (ATRE) Reaction for the Synthesis of Fluoroalkylated Alkenes Using DMA as Electron-Donor

Molecules, 2020, 25, 508

4.9

Q2

贺春阳

119

Translational incorporation of modified phenylalanines and tyrosines during cell-free protein synthesis

RSC Adv. 2020, 10, 11013-11023

4.0

Q2

王中强

120

Synthesis of chromone-containing polycyclic compounds via palladium-catalyzed [2+2+1] annulation

Org. Biomol. Chem. 2020, 18, 1112-1116

3.9

Q1

韩文勇，陈永正

121

A general and green fluoroalkylation reaction promotedvianoncovalent interactions between acetone and fluoroalkyl iodides

Chem. Commun. 2020, 56, 1815-1818

6.1

Q1

贺春阳

122

Visible light promoted deaminative difluoroalkylation of aliphatic amines with difluoroenoxysilanes

Chem. Commun. 2020, 56, 14247-14250

6.1

Q1

贺春阳

123

Catalyst-Free and Visible Light Promoted Aminofluoroalkylation of Unactivated Alkenes: An Access to Fluorinated Aziridines

Adv. Synth. Catal. 2020, 362, 2604-2608

6.0

Q1

贺春阳，赵亮

124

Efficient Assembly of Molecular Complexity Enabled by Palladium-Catalyzed Heck Coupling/C(sp2)−H Activation/ C(sp3)−H Activation Cascade

Adv. Synth. Catal. 2020, 362, 3655-3661

6.0

Q1

韩文勇，陈永正

125

Synthesis  of Chiral 5-Aryl-2-oxazolidinones via Halohydrin Dehalogenase-Catalyzed Enantio-and Regioselective Ring-Opening of Styrene Oxides

Adv. Synth. Catal. 2020, 362, 1201-1207

6.0

Q1

陈永正

126

Visible-Light-Induced Radical Defluoroborylation of Trifluoromethyl Alkenes: An Access to gem-Difluoroallylboranes

Adv. Synth. Catal. 2020, 362, 2990-2996

6.0

Q1

刘小卒，刘培均

127

Iron-Catalyzed Silylation of (Hetero)aryl Chlorides with Et(3)SiBpin

Org. Lett. 2020, 22, 2816-2821

6.1

Q1

贺春阳，李晓飞，冯章

128

Identification of novel quinoline analogues bearing thiazolidinones as potent kinase inhibitors for the treatment of colorectal cancer

Eur. J. Med. Chem. 2020, 204, 112643.

7.1

Q1

祁宝辉

129

Discovery of N1-(4-((7-(3-(4-ethylpiperazin-1-yl)propoxy)-6-methoxyquinolin-4-yl)oxy)-3,5-difluorophenyl)-N3-(2-(2,6-difluorophenyl)-4-oxothiazolidin-3-yl)urea as a multi-tyrosine kinase inhibitor for drug-sensitive and drug-resistant cancers treatment

Eur. J. Med. Chem. 2019, 163, 10-27.

7.1

Q1

祁宝辉

130

Cascade bio-hydroxylation and dehalogenation for one-pot enantioselective synthesis of optically active β-halohydrins from halohydrocarbons

Green Chem. 2019, 21, 4324-4328

11.0

Q1

陈永正

131

Sulfated polysaccharide JCS1S2 inhibits angiogenesis via targeting VEGFR2/VEGF and blocking VEGFR2/Erk/VEGF signaling

Carbohydr. Polym. 2019, 207, 502-509.

10.7

Q1

丁侃

132

2,2-Bifunctionalization of Norbornene in Palladium-Catalyzed Domino Annulation

Org. Lett. 2019, 21, 21, 8857–8860

6.1

Q1

韩文勇，陈永正

133

Ex Situ Generation of Difluorodiazoethane (CF2HCHN2): Application in the Regioselective Synthesis of CF2HContaining Pyrazoles

Org. Lett. 2019, 21, 21, 8751–8755

6.1

Q1

韩文勇，陈永正

134

Organophosphine-Catalyzed Difluoroalkylation of Alkenes

Org. Lett. 2019, 21, 17, 6705–6709

6.1

Q1

贺春阳

135

Palladium-Catalyzed Cross-Coupling of Unactivated Alkylzinc Reagents with 2-Bromo-3,3,3-Trifluoropropene: A New Access to Diversified Fluorinated Amino Acids

Chem. Commun. 2019, 55, 3705-3708

6.1

Q1

贺春阳，张新刚

136

Visible Light Promoted Fluoroalkylation of Alkenes and Alkynes Using 2-Bromophenol as a Catalys

Chem. Commun. 2019, 55, 12259-12262

6.1

Q1

张新刚，贺春阳

137

Regioselective Ring-Opening of Styrene Oxide Derivatives Using Halohydrin Dehalogenase for Synthesis of 4-Aryloxazolidinones

Adv. Synth. Catal. 2019, 361, 4651-4655

6.0

Q1

陈永正

138

139

Organocatalyzed Asymmetric Dearomative Aza-Michael/Michael Addition Cascade of 2-Nitrobenzofurans and 2-Nitrobenzothiophenes with 2-Aminochalcones

J. Org. Chem. 2019, 84, 4381-4391.

4.2

Q1

周晓建，陈永正，袁伟成

140

Cobalt-catalyzed C2α-acyloxylation of 2-substituted Indoles with Tert-butyl Peresters

Org. Biomol. Chem. 2019, 17, 3343-3347

3.9

Q1

刘小卒，刘培均

141

Silver-promoted decarboxylative radical addition/annulation of oxamic acids with gem-difluoroolefins: concise access to CF2-containing 3,4-dihydroquinolin-2-ones

Org. Biomol. Chem. 2019, 17, 8527-8532

3.9

Q1

刘培均，刘小卒

142

Identification of MsrA homologues for the preparation of (R)-sulfoxides at high substrate concentrations

Org. Biomol. Chem. 2019, 17, 3381-3388

3.9

Q2

陈永正

143

Highly alpha-position regioselective ring-opening of epoxides catalyzed by halohydrin dehalogenase from Ilumatobacter coccineus: a biocatalytic approach to 2-azido-2-aryl-1-ols

RSC Adv. 2019, 9, 16418-16422

4.0

Q2

万南微，陈永正

144

Metal-Free Photoinduced Transformation of Aryl Halides and Diketones into Aryl Ketones

Eur. J. Org. Chem. 2019, 2019, 2721-2724

3.3

Q2

姚秋丽

145

A Palladium-Catalyzed Decarboxylative Heck-Type Reaction of Disubstituted Vinylphosphonates in the Stereoselective Synthesis of Trisubstituted Vinylphosphonates

Eur. J. Org. Chem. 2019, 2019, 5656-5661

3.3

Q2

姚秋丽

146

The Photoinduced Metal-Free hydrotrifluoromethylation of Vinyl Phosphonates or Phosphine Oxides.

Eur. J. Org. Chem. 2019, 2019, 7475-7482

3.3

Q2

姚秋丽

147

Synthesis of chiral spiro-cyclopentene/cyclopentadiene-oxindoles through an asymmetric [3 + 2] cycloaddition of isatin-derived  MBH carbonates and β,γ-unsaturated α-keto esters

Tetrahedron, 2019, 75, 2971-2979

2.4

Q2

崔宝东，陈永正

148

Thiourea-catalyzed asymmetric domino Michael-cyclization reaction of 3-isothiocyanato oxindoles with beta,gamma-unsaturated alpha-keto esters for the synthesis of spirocyclic oxindoles

Tetrahedron 2019, 75, 2155-2161.

2.4

Q2

陈永正，袁伟成

149

Discovery of thiazolidin-4-one urea analogues as novel multikinase inhibitors that potently inhibit FLT3 and VEGFR2

Bioorg. Med. Chem. 2019, 27, 2127-2139.

3.5

Q3

祁宝辉

150

Optimization and biological evaluation of nicotinamide derivatives as Aurora kinase inhibitors

Bioorg. Med. Chem. 2019, 27, 3825-3835.

3.5

Q3

祁宝辉

151

Effects and mechanisms of Danshen-Shanzha herb-pair for atherosclerosis treatment using network pharmacology and experimental pharmacology

Journal of Ethnopharmacology, 2019, 229, 104-114

3.7

Q1

张建永

152

Deracemization of Phenyl-Substituted 2-Methyl-1,2,3,4TetrahydroquinolinesbyaRecombinant Monoamine Oxidase from Pseudomonas monteilii ZMU-T01

Chemcatchem, 2018,  10, 2374-2377

4.7

Q3

陈永正, 邓国忠

153

A Protocol for the Synthesis of CF2HContaining
Pyrazolo[1,5c]quinazolines from 3Ylideneoxindoles and in Situ Generated CF2HCHN2

Journal of Organic Chemistry , 2018, 83, 6556-6565

4.8

Q2

陈永正, 汪建树

154

AcOH-catalyzed aza-Michael addition/N-nitrosation: An efficient
approach to CF2HCH2-containing N-nitrosoamines

Tetrahedron, 2018, 74,  3904-3911

2.4

Q3

陈永正, 汪建树

155

Asymmetric [3 + 2] Cycloaddition Reaction of Isatin-Derived MBH Carbonates with 3Methyleneoxindoles: Enantioselective Synthesis of 3,3′-Cyclopentenyldispirooxindoles Incorporating Two Adjacent Quaternary Spirostereocenters

Journal of Organic Chemistry, 2018, 83, 10465-10475

4.8

Q2

陈永正, 陈羽

156

Biocatalytical Asymmetric Sulfoxidation by Identifying Cytochrome P450 from Parvibaculum Lavamentivorans DS-1

Chemcatchem, 2018, 10, 5410-5413

4.7

Q3

陈永正, 伍开琳

157

Identification and characterization of a highly S-enantioselective halohydrin
dehalogenase from Tsukamurella sp. 1534 for kinetic resolution of
halohydrins

Bioorganic Chemistry, 2018, 81, 529-535

3.9

Q2

陈永正, 万南微

158

Catalyst-free and visible light promoted trifluoromethylation and perfluoroalkylation of uracils and cytosines

Chemical Communications, 2018,54,1359-7345

6.2

Q2

黄洋，贺春阳

159

A Protocol for the Synthesis of CF2HContaining
Pyrazolo[1,5c]quinazolines from 3Ylideneoxindoles and in Situ
Generated CF2HCHN2

Journal of Organic Chemistry, 2018, 83, 6556−6565

4.7

Q2

陈永正,  韩文勇

160

Base-promoted 1,3-dipolar cycloaddition reaction of nitrile oxides with
methyl 1,4-dioxo-1,4-dihydronaphthalene-2-carboxylate for the
construction of naphtho[2,3-d]isoxazole-4,9(3aH,9aH)-diones

Tetrahedron Letters, 2018,  59, 2622–2626

2.1

Q3

陈永正，袁伟成

161

Zn-Catalyzed Diastereo- and Enantioselective Dearomative
[3+2] Cycloaddition Reaction of 2-Nitroindoles and 2-
Nitrobenzothiophenes

Advanced Synthesis & Catalysis, 2018, 360, 1 –7

5.5

Q2

陈永正，袁伟成

162

Organocatalytic Asymmetric [3 + 2] Cycloaddition of N2,2,2-
Trifluoroethylisatin Ketimines with βTrifluoromethyl ElectronDeficient
Alkenes: Access to Vicinally Bis(trifluoromethyl)-
Substituted 3,2′-Pyrrolidinyl Spirooxindoles

Organic Letters, 2018, 20, 4453−4457

6.5

Q1

陈永正，袁伟成，游勇

163

Biocatalytic Preparation of Chiral Sulfoxides through
Asymmetric Reductive Resolution by Methionine Sulfoxide
Reductase A

ChemCatChem 2018, 10, 3284-3290

4.7

Q2

陈永正，杨思怡

164

Asymmetric [3 + 2] Cycloaddition Reaction of Isatin-Derived MBH
Carbonates with 3Methyleneoxindoles: Enantioselective Synthesis
of 3,3′-Cyclopentenyldispirooxindoles Incorporating Two Adjacent
Quaternary Spirostereocenters

Journal of Organic Chemistry, 2018, 83, 10465-10475

4.7

Q2

陈永正，崔宝东

165

Enantioselective synthesis of 1,2,3,4-
tetrahydroquinoline-4-ols and
2,3-dihydroquinolin-4(1H)-ones via a sequential
asymmetric hydroxylation/diastereoselective
oxidation process using Rhodococcus equi

ZMU-LK19†

Organic & Biomolecular Chemistry, 2017, 15, 3580–3584

3.5

Q2

陈永正

166

Chemoenzymatic synthesis of b-hydroxyl-sulfoxides by a two-step
reaction of enzymatic reduction using Pseudomonas monteilii species
and sulfoxidation with chiral titanium complexe

Tetrahedron, 2017, 73 5200-5206

2.3

Q3

陈永正，崔宝东

167

Synthesis of Phenanthridines through Palladium-Catalyzed
Cascade Reaction of 2-Halo-N-Ms-arylamines with Benzyl
Halides/Sulfonates

European Journal of Organic Chemistry, 2017, 5, 996-1003

2.8

Q3

陈永正, 杨思怡

168

Biocatalytic a-Oxidation of Cyclic Amines and
N-Methylanilines for the Synthesis of Lactams and
Formamides

ChemCatChem, 2017, 9, 937-940

4.8

Q2

陈永正, 郑代军

169

Sequential Nucleophilic C(sp3)-Benzylation/C(sp2)–H Arylation for the Synthesis of Spiro[oxindole-3,5′-pyrrolo[2,1-a]isoquinolines]

European Journal of Organic Chemistry, 2017,  6, 3179-3186  

2.8

Q3

陈永正,  张婷磊

170

Diastereoselective [3 + 2] cycloaddition of
3-ylideneoxindoles with in situ generated
CF2HCHN2: syntheses of CF2H-containing
spirooxindoles

Organic &
Biomolecular Chemistry, 2017, 15, 5571-5578

3.4

Q3

陈永正,韩文勇

171

Synthesis of 2,3’-spirobi[indolin]-2-ones enabled
by a tandem nucleophilic benzylation/C(sp2)–N
cross-coupling reaction sequence

Organic &
Biomolecular Chemistry, 2017

3.4

Q3

陈永正, 单静

172

Syntheses of CF2H-containing spirocyclopropyloxindoles from in situ
generated CF2HCHN2 and 3-ylideneoxindoles

Tetrahedron, 2017, 39,  5806-5812

2.6

Q3

陈永正, 赵佳

173

174

Development of an indicator for the direct visualization of radical intermediates in organic reactions

Chemical Communications, 2017,53,11225-11228

6.3

Q2

姚秋丽

175

An unprecedented protocol for the synthesis of
3-hydroxy-3-phenacyloxindole derivatives with
indolin-2-ones and α-substituted ketones†

Organic & Biomolecular Chemistry, 2016, 14, 1395–1401 |

3.6

Q2

陈永正，白玫

176

Organocatalytic Asymmetric Mannich Reaction of
3Hydroxyoxindoles/3-Aminooxindoles with in Situ Generated

NBoc-Protected Aldimines for the Synthesis of Vicinal Oxindole−

Diamines/Amino Alcohols

Journal of Organic Chemistry, 2016, 81, 5270−5277

4.8

Q2

陈永正, 单静

177

Bio-mediated oxidative resolution of racemic 2-substituted 1,2,3,4-
tetrahydroquinolines

Tetrahedron Letters, 2016,  2403–2405

2.3

Q3

陈永正, 秦磊

178

RNA-seqtranscriptomeanalysisofaPseudomonas
strainwithdiversiffedcatalyticpropertiesgrowth
underdifferentculturemedium

MicrobiologyOpen 2016, 5, 626–636

2.1

Q3

陈永正, 杨加伟

179

Bioreduction of the C]C double bond with Pseudomonas monteilii

ZMU-T17: one approach to 3-monosubstituted oxindoles

Tetrahedron, 2016, 72,  3098-3104

2.6

Q3

陈永正, 赵佳

180

Novozyme 435 lipase mediated enantioselective kinetic resolution:
a facile method for the synthesis of chiral tetrahydroquinolin-4-ol
and tetrahydro-1H-benzo[b]azepin-5-ol derivatives

Tetrahedron 2015, 714, 4738-4744

2.6

Q3

陈永正, 周晓建

181

Palladium-Catalyzed Nucleophilic Substitution/C−H Activation/
Aromatization Cascade Reaction: One Approach To Construct
6Unsubstituted Phenanthridines

Journal of Organic Chemistry, 2015, 80, 11580−11587

4.8

Q2

陈永正,  韩文勇